Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1982 Aug;37(2):837–839. doi: 10.1128/iai.37.2.837-839.1982

Isolation and Characterization of Pneumolysin-Negative Mutants of Streptococcus pneumoniae

Mary K Johnson 1, David Hamon 1, Gloria K Drew 1
PMCID: PMC347608  PMID: 6922089

Abstract

Pneumolysin-negative mutants of Streptococcus pneumoniae were isolated after mutagenesis with ethyl methane sulfonate. Though totally devoid of pneumolysin, these strains produced alpha hemolysis on blood agar when incubated aerobically. It is concluded that the alpha hemolysis typical of pneumococci is unrelated to their pneumolysin content.

Full text

PDF
837

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barany F., Tomasz A. Genetic transformation of Streptococcus pneumoniae by heterologous plasmid deoxyribonucleic acid. J Bacteriol. 1980 Nov;144(2):698–709. doi: 10.1128/jb.144.2.698-709.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Johnson M. K. Properties of purified pneumococcal hemolysin. Infect Immun. 1972 Nov;6(5):755–760. doi: 10.1128/iai.6.5.755-760.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES