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Indian Journal of Microbiology logoLink to Indian Journal of Microbiology
. 2009 Mar 25;48(3):397–400. doi: 10.1007/s12088-008-0047-9

Metabolism of lysine-chromium complex in Saccharomyces cerevisiae

K S Karthikeyan 1, H Polasa 1, K Sivarama Sastry 1, Gopal Reddy 1,
PMCID: PMC3476769  PMID: 23100739

Abstract

Saccharomyces cerevisiae which cannot utilize lysine as a sole nitrogen source is shown to metabolize a Lysine 3 Cr3+ (1:1) complex synthesized, as a combined nitrogen and carbon source. It induces rapid uptake of lysine and prevents loss of viability, in contrast with free lysine. That complexation with trivalent chromium has the effect of profoundly influencing intracellular distribution and metabolism of the liganded amino acid is demonstrated.

Keywords: Saccharomyces cerevisiae, Lysine, Lysine-chromium complex, Metabolism

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