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. 2012 Jul 1;3(4):377–388. doi: 10.4161/viru.21087

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Figure 2. Breaching of gut epithelia by Salmonella. The mode of entry of Salmonella in gut lumen varies according to type of cell encountered on the gut epithelium. The M cells take up the bacteria by means of receptor mediated endocytosis, whereas dendritic cells engulf them by phagocytosis. The membrane of epithelial cells is modified by the action of SPI1 to facilitate the entry of bacteria. Once inside the gut lumen, Salmonella is being taken up by macrophages, T cells, B cells, neutrophils, etc.