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. 1982 Dec;38(3):1304–1308. doi: 10.1128/iai.38.3.1304-1308.1982

Intracellular replication of Leishmania tropica in mouse peritoneal macrophages: amastigote infection of resident cells and inflammatory exudate macrophages.

A H Fortier, D L Hoover, C A Nacy
PMCID: PMC347892  PMID: 7152674

Abstract

C3HeB/FeJ peritoneal exudate cells elicited by a variety of sterile inflammatory agents were exposed to Leishmania tropica amastigotes in vitro. Cytochemical characterization of cells that contained intracellular parasites suggested that young, peroxidase-positive macrophages were more susceptible to infection by amastigotes than more mature cells. Replication of the parasite in these younger cells, however, was similar to that observed in resident peritoneal macrophages.

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Selected References

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