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. Author manuscript; available in PMC: 2013 Dec 6.
Published in final edited form as: Neuroscience. 2012 Sep 15;225:130–139. doi: 10.1016/j.neuroscience.2012.08.042

Fig. 4.

Fig. 4

Reduced D1R and D2R coexpression in NAc shell and caudate putamen of juvenile rats. (A) Quantification of the number of D1R-expressing neurons per 300 μm2 area (N=16-25 sections/region). (B) The proportion of D1R-expressing neurons also expressing the D2R. Adults exhibited a significantly greater proportion of D1R and D2R coexpressing neurons in NAc shell and CP, but not NAc core (C) D1R and D2R formed D1-D2 receptor heteromers as determined by FRET. FRET signal indicated equivalent FRET efficiencies between juvenile and adult rats in NAc and CP (N=25-62 neurons/region). Data expressed as mean ± SEM. *P<0.05 Student’s ttest.