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. 1983 Jan;39(1):476–479. doi: 10.1128/iai.39.1.476-479.1983

Suppression of Murine Lymphocyte Mitogen Responses by Exopolysaccharide from Capnocytophaga ochracea

Ronald W Bolton 1, John K Dyer 1
PMCID: PMC347968  PMID: 6822434

Abstract

An extracellular polysaccharide was purified from culture supernatants of Capnocytophaga ochracea 25, a gram-negative bacillus associated with human periodontal disease. The extracellular polysaccharide suppressed in vitro mitogenic responses of murine splenic lymphocytes to concanavalin A and lipopolysaccharide. This suppression wad dose dependent, persisted up to 120 h, and was not caused by direct toxicity of the extracellular polysaccharide.

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Selected References

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