Abstract
An F-lac plasmid from Escherichia coli was transferred to virulent Yersinia pestis, resulting in the repression of virulence. The Y. pestis F-lac clones retained all of the known virulence traits but were avirulent and calcium independent. Every lac segregant derived from the F-lac clones was fully virulent and calcium dependent.
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Selected References
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- Albizo J. M., Surgalla M. J. Specific identification of fraction I-positive Pasteurella pestis colonies on antiserum-agar plates. Appl Microbiol. 1968 Apr;16(4):649–655. doi: 10.21236/ad0835494. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Albizo J. M., Surgalla M. J. Use of the antiserum-agar plate technique for specific identification and isolation of Pasteurella pestis. Appl Microbiol. 1968 Aug;16(8):1114–1119. doi: 10.1128/am.16.8.1114-1119.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BACON G. A., BURROWS T. W. The basis of virulence in Pasteurella pestis: an antigen determining virulence. Br J Exp Pathol. 1956 Oct;37(5):481–493. [PMC free article] [PubMed] [Google Scholar]
- BRUBAKER R. R., SURGALLA M. J. Genotypic alterations associated with avirulence in streptomycin-resistant Pasteurella pestis. J Bacteriol. 1962 Oct;84:615–624. doi: 10.1128/jb.84.4.615-624.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BRUBAKER R. R., SURGALLA M. J. Pesticins. II. Production of pesticin I and II. J Bacteriol. 1962 Sep;84:539–545. doi: 10.1128/jb.84.3.539-545.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Beesley E. D., Brubaker R. R., Janssen W. A., Surgalla M. J. Pesticins. 3. Expression of coagulase and mechanism of fibrinolysis. J Bacteriol. 1967 Jul;94(1):19–26. doi: 10.1128/jb.94.1.19-26.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ben-Gurion R., Shafferman A. Essential virulence determinants of different Yersinia species are carried on a common plasmid. Plasmid. 1981 Mar;5(2):183–187. doi: 10.1016/0147-619x(81)90019-6. [DOI] [PubMed] [Google Scholar]
- Brubaker R. R. The genus Yersinia: biochemistry and genetics of virulence. Curr Top Microbiol Immunol. 1972;57:111–158. doi: 10.1007/978-3-642-65297-4_4. [DOI] [PubMed] [Google Scholar]
- Ferber D. M., Brubaker R. R. Plasmids in Yersinia pestis. Infect Immun. 1981 Feb;31(2):839–841. doi: 10.1128/iai.31.2.839-841.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GINOZA H. S., MATNEY T. S. TRANSMISSION OF A RESISTANCE TRANSFER FACTOR FROM ESCHERICHIA COLI TO 2 SPECIES OF PASTEURELLA. J Bacteriol. 1963 May;85:1177–1178. doi: 10.1128/jb.85.5.1177-1178.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gemski P., Lazere J. R., Casey T. Plasmid associated with pathogenicity and calcium dependency of Yersinia enterocolitica. Infect Immun. 1980 Feb;27(2):682–685. doi: 10.1128/iai.27.2.682-685.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gemski P., Lazere J. R., Casey T., Wohlhieter J. A. Presence of a virulence-associated plasmid in Yersinia pseudotuberculosis. Infect Immun. 1980 Jun;28(3):1044–1047. doi: 10.1128/iai.28.3.1044-1047.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HIGUCHI K., KUPFERBERG L. L., SMITH J. L. Studies on the nutrition and physiology of Pasteurella pestis. III. Effects of calcium ions on the growth of virulent and avirulent strains of Pasteurella pestis. J Bacteriol. 1959 Mar;77(3):317–321. doi: 10.1128/jb.77.3.317-321.1959. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HIGUCHI K., SMITH J. L. Studies on the nutrition and physiology of Pasteurella pestis. VI. A differential plating medium for the estimation of the mutation rate to avirulence. J Bacteriol. 1961 Apr;81:605–608. doi: 10.1128/jb.81.4.605-608.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MARTIN G., JACOB F. [Transfer of the sex episome from Escherichia coli to Pasteurella pestis]. C R Hebd Seances Acad Sci. 1962 May 14;254:3589–3590. [PubMed] [Google Scholar]
- Portnoy D. A., Falkow S. Virulence-associated plasmids from Yersinia enterocolitica and Yersinia pestis. J Bacteriol. 1981 Dec;148(3):877–883. doi: 10.1128/jb.148.3.877-883.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Portnoy D. A., Moseley S. L., Falkow S. Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis. Infect Immun. 1981 Feb;31(2):775–782. doi: 10.1128/iai.31.2.775-782.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Straley S. C., Brubaker R. R. Localization in Yersinia pestis of peptides associated with virulence. Infect Immun. 1982 Apr;36(1):129–135. doi: 10.1128/iai.36.1.129-135.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Surgalla M. J., Beesley E. D. Congo red-agar plating medium for detecting pigmentation in Pasteurella pestis. Appl Microbiol. 1969 Nov;18(5):834–837. doi: 10.1128/am.18.5.834-837.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zink D. L., Feeley J. C., Wells J. G., Vanderzant C., Vickery J. C., Roof W. D., O'Donovan G. A. Plasmid-mediated tissue invasiveness in Yersinia enterocolitica. Nature. 1980 Jan 10;283(5743):224–226. doi: 10.1038/283224a0. [DOI] [PubMed] [Google Scholar]