Table 1.
No Diabetes | Diabetes | |
---|---|---|
N | 3,856 | 103 |
Male | 1,876 | 40 |
Female | 1,980 | 63 |
Age (years) | 13.0 ± 3.8 | 14.5 ± 3.0 |
Duration of diabetes (years)* | - | 1.3(0-2.1) |
BMI (kg/m2) | 25.7 ± 7.3 | 34.9 ± 7.4 |
BMI SDS | 1.34±1.01 | 2.25±0.50 |
HbA1c (%) | 5.0 ± 0.5 | 8.1 ± 3.0 |
2-hour plasma glucose (mmol/L) | 5.7 ± 1.3 | 16.9 ± 6.0 |
MAP (mmHg) | 75.9 ± 10.1 | 83.6 ± 9.9 |
Serum creatinine (μmol/L) | 56 ± 15 | 55 ± 11 |
Estimated GFR† | 141±21 | 154±27 |
ACR (mg/g)‡ | UD (UD-8.9) | 6.6 (UD-21.9) |
Percentiles of ACR (mg/g) by age group | ||
Age 5-9 years | N=982 | N=4§ |
50th | UD | |
75th | 11.4 | |
95th | 51.3 | |
Age 10-14 years | N=1,469 | N=48 |
50th | UD | 8.5 |
75th | 9.1 | 23.6 |
95th | 48.3 | 190.2 |
Age 15-19 years | N=1,405 | N=51 |
50th | UD | 5.2 |
75th | 7.4 | 20.9 |
95th | 27.7 | 210.0 |
Abbreviations: ACR, urinary albumin-to-creatinine ratio; BMI, body mass index; BMI SDS, body mass index standard deviation score; GFR, glomerular filtration rate; MAP, mean arterial pressure; UD, undetectable albuminuria.
Statistics are mean and standard deviation
%median (25th-75th percentile).
Glomerular filtration rate was estimated using the Schwartz equation [19] in subjects less than 18 years of age and by the 4-variable Modification of Diet in Renal Disease (MDRD) study equation [20] in those 18 years and older.
Percentiles not reported due to the small number of subjects.