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Journal of Biological Physics logoLink to Journal of Biological Physics
. 2005 Jan;31(1):73–85. doi: 10.1007/s10867-005-6732-6

Orientation of Red Blood Cells and Rouleaux Disaggregation in Interference Laser Fields

J V Kruchenok 1,, S B Bushuk 1, G I Kurilo 1, N A Nemkovich 1, A N Rubinov 1
PMCID: PMC3482096  PMID: 23345885

Abstract

The effect of interference laser fields on red blood cells (RBCs) was investigated both theoretically and experimentally. The optical trapping and orientation of individual RBC in interference fringes were observed. It was found that RBC rouleaux undergo disaggregation under the action of interference laser fields. To describe the effect of RBC orientation in interference fringes, we used the equation for torque exerted on a discoid dielectric particle in a gradient light field. The experimental results are in agreement with the predictions of the developed theoretical model.

Key words: interferometric trapping, red blood cell orientation, rouleau disaggregation

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