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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1980 Jan;77(1):385–388. doi: 10.1073/pnas.77.1.385

Identification of an adhesion factor for chondrocytes.

A T Hewitt, H K Kleinman, J P Pennypacker, G R Martin
PMCID: PMC348275  PMID: 6928630

Abstract

The attachment of chondrocytes to collagen substrates is stimulated by serum but not by fibronectin. The active material in serum was partially purified and was shown to be a protein by its sensitivity to trypsin and heat and its chromatographic properties. This factor, which we have named chondronectin, is distinct from fibronectin and does not stimulate fibroblast attachment. Because material with similar attachment-enhancing activity is produced by chondrocytes and is extractable from cartilage, chondronectin may be a chondrocyte-specific attachment protein.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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