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. 1980 Mar;77(3):1580–1582. doi: 10.1073/pnas.77.3.1580

Autosomal dominant aniridia: probable linkage to acid phosphatase-1 locus on chromosome 2.

R E Ferrell, A Chakravarti, H M Hittner, V M Riccardi
PMCID: PMC348540  PMID: 6929510

Abstract

Maximum likelihood analysis for linkage between autosomal dominant aniridia and 12 biochemical and serological markers in a single large family showed a probable linkage between autosomal dominant aniridia and the enzyme acid phosphatase-1. The presence of an autosomal dominant aniridia gene linked to acid phosphatase-1 on chromosome arm 2p and the existence of an aniridia syndrome resulting from deletion of band 13 of the short arm of chromosome 11 establishes a chromosome basis for genetic heterogeneity of aniridia phenotypes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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