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. 1980 Apr;77(4):2134–2137. doi: 10.1073/pnas.77.4.2134

Genes for three Drosophila heat-shock-induced proteins at a single locus.

S C Wadsworth, E A Craig, B J McCarthy
PMCID: PMC348666  PMID: 6769119

Abstract

Two plasmids containing cDNA inserts complementary to the messenger RNAs for the 26,000 and 23,000 molecular weight heat-shock-induced proteins from Drosophila melanogaster were identified. Both of these probes hybridized to a site of a major heat-shock-induced puff, 67B. Hybridization by the gel transfer technique with genome DNA that had been cleaved by a restriction endonuclease indicated that the two genes are closely linked. This expectation was validated through isolation of a DNA fragment generated by BamHI endonuclease containing genes for the 26,000 and 23,000 molecular weight heat-shock-induced proteins and also a gene encoding the 27,000 molecular weight heat-shock-induced protein.

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Selected References

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