. 2012 Mar 28;64(6):687–699. doi: 10.1007/s10616-012-9449-y

Table 2.

Hepatoprotective effect of Gln on TCDD induced toxicity in cultured rat hepatocytes by the liver MN assay

Treatments	MNHEP (%)/2000 HEP
Control	0.25 ± 0.08^a
TCDD 1	0.86 ± 0.27^c
TCDD 2	1.74 ± 0.35^d
Gln 1	0.26 ± 0.14^a
Gln 2	0.29 ± 0.09^a
Gln 3	0.22 ± 0.11^a
TCDD 1 + Gln 1	0.79 ± 0.27^c
TCDD 1 + Gln 2	0.61 ± 0.22^bc
TCDD 1 + Gln 3	0.43 ± 0.19^b
TCDD 2 + Gln 1	1.39 ± 0.45^cd
TCDD 2 + Gln 2	1.01 ± 0.47^cd
TCDD 2 + Gln 3	0.88 ± 0.43^c

HEP hepatocyte, MNHEPs number of micronucleated hepatocytes. TCDD 1: 0.005 mM TCDD; TCDD 2: 0.01 mM TCDD; Gln 1: 0.5 mM l-glutamine; Gln 2: 1 mM l-glutamine; Gln 3: 2 mM l-glutamine; means (n = 6) in the table followed by the different letters present significant differences from each other at the p < 0.05 level