Table 5.

Estimates of the per patient-year incidence of ACS and pain that required hospitalization among children in the SIT Trial according to (GT)_n genotype class

	S/S*	S/L + L/L*	Unadjusted rate ratio	95% CI	Adjusted rate ratio†	95% CI
ACS	0.038	0.147	0.26	0.09-0.75	0.28	0.10-0.81
Pain	0.600	0.628	0.96	0.60-1.51	1.03	0.65-1.65

^*HMOX1 (GT)_n allele classes defined by number of repeats: S ≤ 25 repeats; and L > 25 repeats.

^†Adjusted for sex, ever had asthma, percentage of fetal hemoglobin, and α-globin gene deletion status.