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. 1981 Oct;78(10):6286–6289. doi: 10.1073/pnas.78.10.6286

Reactivation of chicken erythrocyte nuclei in heterokaryons results in expression of adult chicken globin genes.

S Linder, S H Zuckerman, N R Ringertz
PMCID: PMC349023  PMID: 6796958

Abstract

Activation of chicken globin gene transcription has been demonstrated in chicken erythrocyte--rat L6 myoblast heterokaryons. The globin mRNA is polyadenylylated and is translated into adult chicken alpha A-, alpha D-, and beta-globin polypeptides. No fetal globin mRNA or globin polypeptides were detected. Heterokaryons between chicken erythrocytes and mouse neuroblastoma cells or hamster BHK cells also synthesized adult chicken globins.

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Selected References

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