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. 1981 Oct;78(10):6290–6294. doi: 10.1073/pnas.78.10.6290

5-Azacytidine induction of mouse endogenous type C virus and suppression of DNA methylation.

O Niwa, T Sugahara
PMCID: PMC349024  PMID: 6171816

Abstract

5-Azacytidine was found to induce the expression of BALB:virus-1 and BALB:virus-2 from K-BALB cells and ecotropic endogenous virus from AKR2B cells. Efficiency of the induction was high and comparable to that by 5-bromodeoxyuridine. The level of methylcytosine in newly synthesized DNA was drastically decreased when K-BALB cells were treated with 5-azacytidine. There was an inverse relationship between the level of DNA modification and the frequency of virus expression.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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