Table 6B.

Spermidine repressed genes involved in various stress response^τ

Gene names	Annoted functions	Fold change
HSP12	Plasma membrane localized protein, induced by heat shock, oxidative stress, osmotic stress, glucose depletion	−2.8
HSP104	Responsive to stress (heat, ethanol, and sodium arsenite), involved in [PSI+] propagation	−3.4
HAP4	Subunit of the heme-activated, glucose-repressed Hap-protein complex, a transcriptional activator of respiratory gene expression	−3
GPD1	NAD-dependent glycerol-3-phosphate dehydrogenase, essential for growth under osmotic stress	−2.8
ROX1	Heme-dependent repressor of hypoxic genes, responsible for DNA bending activity	−3.4
GAD1	Glutamate decarboxylase, converts glutamate into gamma-aminobutyric acid, involved in response to oxidative stress	−3.4
SDP1	Stress-inducible dual-specific MAP kinase phosphatase	−2.7
CYC7	Cytochrome c isoform 2, expressed under hypoxic condition	−5.3
CTT1	Cytosolic catalase T, has a role in protection from oxidative damage by hydrogen peroxide	−6.6
GPX2	Glutathione peroxidase, induced by glucose starvation, protects cells from phospholipids hydroperoxides and non-phospholipid peroxides during oxidative stress	−1.8