Skip to main content
. Author manuscript; available in PMC: 2012 Nov 7.
Published in final edited form as: Metabolism. 2011 Jan 19;60(8):1070–1080. doi: 10.1016/j.metabol.2010.11.003

Table 2.

Effect of hyperglycemia on plasma and artery lipids in control and STZ-DM monkeysa

Control (n=10) STZ-DM (n=10) p-value
Plasma lipids
 Total cholesterol (mg/dl) 233 ± 25 270 ± 32 0.91
 ApoB cholesterol (mg/dl) 189 ± 29 227 ± 35 0.94
 HDL cholesterol (mg/dl) 45 ± 5 43 ± 5 0.74
 Triglycerides (mg/dl) 32 ± 4 152 ± 58 <0.05
 Free fatty acids (mEq/l) 0.68 ± 0.10 0.80 ± 0.16 0.72
Carotid artery lipids
 Total cholesterol (μg/mg protein) 10.6 ± 3.2 14.2 ± 6.5 0.63
 Free cholesterol (μg/mg protein) 5.9 ± 1.0 6.4 ± 2.4 0.85
 Cholesterol ester (μg/mg protein) 5.5 ± 2.2 8.0 ± 4.1 0.53
 Lipid peroxides (nmol/mg) 5.06 ± 1.24 4.73 ± 1.72 0.58
Aortic intimal area (mm2) 0.86 ± 0.30 0.83 ± 0.33 0.94
a

Fasting blood samples and carotid artery lipids were obtained from control and streptozotocin-treated monkeys four weeks after diabetes induction. Aortic intimal area was determined by computer morphometric analysis. Data are presented as the mean ± SEM (n = 10 animals per group) together with respective T-test or ANCOVA p-values.