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. 1981 Nov;78(11):7219–7223. doi: 10.1073/pnas.78.11.7219

Porcine pituitary dynorphin: complete amino acid sequence of the biologically active heptadecapeptide.

A Goldstein, W Fischli, L I Lowney, M Hunkapiller, L Hood
PMCID: PMC349228  PMID: 6118870

Abstract

The full primary structure of the very potent opioid peptide dynorphin, from porcine pituitary, has been determined. It is (H)Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln(OH). The synthetic peptide with this sequence behaves identically to natural dynorphin in a number of ways, and it has the same potency in the guinea pig ileum myenteric plexus--longitudinal muscle bioassay. The potency is accounted for by the first 13 residues.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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