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. 1981 Dec;78(12):7309–7313. doi: 10.1073/pnas.78.12.7309

Molecular structure of a double helix that has non-Watson—Crick type base pairing formed by 2-substituted poly(A) and poly(U)

Toshio Hakoshima 1, Toshikazu Fukui 1, Morio Ikehara 1, Ken-ichi Tomita 1
PMCID: PMC349255  PMID: 6950376

Abstract

X-ray fiber diffraction studies of duplexes formed by 2-substituted poly(A) and poly(U) provide evidence for the existence of a double helical structure of poly(A)·poly(U) held together by Hoogsteen-type base pairing with parallel chain polarity.

Keywords: x-ray diffraction, nucleic acid, alternative complementarity, molecular evolution, gene processing

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Selected References

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