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Ribbon diagram of the crystal structure (2I5Y) from the YU2 strain showing gp120 inner, outer and bridging sheet colored red, yellow and green, respectively. The mini-protein CD4 mimetic (CD4M33) containing a biphenyl group (purple) binds in the cavity formed at the junction of the three domains. The D1 domain of the 17b Fab is shown in blue. (Rendered with MOE70 )
