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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1980 Jun;77(6):3654–3658. doi: 10.1073/pnas.77.6.3654

Measurement of changes in high-energy phosphates in the cardiac cycle using gated 31P nuclear magnetic renonance.

E T Fossel, H E Morgan, J S Ingwall
PMCID: PMC349676  PMID: 6932041

Abstract

Levels of the high-energy phosphate-containing compounds, ATP and creatine phosphate, and of inorganic phosphate (Pi) were measured as a function of position in the cardiac cycle. Measurements were made on isolated, perfused, working rat hearts through the use of gated 31P nuclear magnetic resonance spectroscopy. Levels of ATP and creatine phosphate were found to vary during the cardiac cycle and were maximal at minimal aortic pressure and minimal at maximal aortic pressure. Pi varied inversely with the high-energy phosphates.

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Selected References

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