Abstract
Myogenic cells release into their culture medium a glycoprotein complex that mediates cellular adhesion. In the absence of calcium this complex has a sedimentation value of 16S; it aggregates in the presence of calcium. The 16S material both agglutinates and increases the rate of cell-substratum adhesion of a myoblast variant and inhibits the adhesion of a nerve-like cell line to culture dishes. It is also a hemagglutinin. The 16S particle is composed of glycosaminoglycans and several proteins, including fibronectin and collagen.
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Selected References
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