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. 1980 Aug;77(8):4610–4613. doi: 10.1073/pnas.77.8.4610

ATP-driven steady-state exchange of monomeric and filamentous actin from Dictyostelium discoideum.

P A Simpson, J A Spudich
PMCID: PMC349894  PMID: 6933508

Abstract

When [35S]actin monomer from the slime mold Dictyostelium discoideum is added in trace amounts to a population of unlabeled Dictyostelium actin molecules assembled to steady state, it rapidly exchanges with the pool of actin filaments. This exchange between monomeric and filamentous actin is dependent on the presence of ATP. In addition, the exchange appears to occur via filament ends, because cytochalasin D, a drug that interacts specifically with actin filament ends to inhibit filament assenbly, inhibits the exchange reaction.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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