Table III.
Pancreatic GPCR Array Data (fold change in tumors relative to normals)
| Gene; Gene Name | Fold Change | p-value |
|---|---|---|
| SSTR2; Somatostatin Receptor 2 | +5.6 | 0.0124 |
| GRPR; Gastrin Releasing Peptide Receptor | −31.0 | 0.00001 |
| VIPR2; Vasoactive Intestinal Peptide Receptor 2 | −25.2 | 0.00002 |
| SCTR; Secretin Receptor | −25.1 | 0.07519 |
| ADORA1; Adenosine A1 Receptor | −21.7 | 0.00007 |
| EDG7; Endothelial Differentiation Gene 7 | −21.5 | 0.0006 |
| PHGDH; Phosphoglycerate Dehydrogenase | −15.3 | 0.0013 |
| NMUR1; Neuromedin U Receptor 1 | −10.3 | 0.0072 |
| GPR120; G-Protein Coupled Receptor 120 | −8.2 | 0.0186 |
| LGR4; Leucine-Rich Repeat Containing G-Protein Coupled Receptor 4 | −7.6 | 0.00003 |
| GPR161; G-Protein Coupled Receptor 161 | −7.3 | 0.00018 |
| PTGER4; Prostaglandin E Receptor 4, Subtype EP4 | −7.3 | 0.0015 |
| BDKRB1; Bradykinin Receptor B1 | −6.6 | 0.0003 |
| CHRM3 ; Cholinergic Receptor, Muscarinic 3 | −6.4 | 0.0002 |
| CCKBR; Cholecystokinin B Receptor | −6.2 | 0.0094 |
| P2RY1; Purinergic Receptor P2Y, G-Protein Coupled, 1 | −5.6 | 0.0186 |
| SMO; Smoothened, Frizzled Family Receptor | −5.4 | 0.0183 |
| IL8RB; Interleukin 8, Receptor Beta | −5.0 | 0.0193 |
| GPRC5B; G-Protein Coupled Receptor, Family C, Group 5, Member B | −5.0 | 0.00007 |