Abstract
Bacterial and vegetable ureases were found to differ in certain important respects. For maximal clinical relevance, in vitro studies on the pathogenic role of urease should use whole bacterial cells of Proteus spp., and urease inhibitors should be assessed without preincubation of enzyme with inhibitor. Urease from Proteus morganii was very different from ureases of other species of Proteus; this factor should be taken into account when infections with P. morganii are being treated.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Andersen J. A. Benurestat, a urease inhibitor for the therapy of infected ureolysis. Invest Urol. 1975 Mar;12(5):381–386. [PubMed] [Google Scholar]
- Andrews P. Estimation of the molecular weights of proteins by Sephadex gel-filtration. Biochem J. 1964 May;91(2):222–233. doi: 10.1042/bj0910222. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burr R. G. Inhibition of urease by miscellaneous ions and compounds. Implications for the therapy of infection-induced urolithiasis. Invest Urol. 1977 Sep;15(2):180–182. [PubMed] [Google Scholar]
- Derrick F. C., Jr, Carter W. C., 3rd Kidney stone disease: evaluation and medical management. Postgrad Med. 1979 Oct;66(4):115-9, 122-5. doi: 10.1080/00325481.1979.11715275. [DOI] [PubMed] [Google Scholar]
- FISHBEIN W. N., CARBONE P. P. UREASE CATALYSIS. II. INHIBITION OF THE ENZYME BY HYDROXYUREA, HYDROXYLAMINE, AND ACETOHYDROXAMIC ACID. J Biol Chem. 1965 Jun;240:2407–2414. [PubMed] [Google Scholar]
- FISHBEIN W. N., WINTER T. S., DAVIDSON J. D. UREASE CATALYSIS. I. STOICHIOMETRY, SPECIFICITY, AND KINETICS OF A SECOND SUBSTRATE: HYDROXYUREA. J Biol Chem. 1965 Jun;240:2402–2406. [PubMed] [Google Scholar]
- Fishbein W. N., Carbone P. P., Hochstein H. D. Acetohydroxamate: bacterial urease inhibitor with therapeutic potential in hyperammonaemic states. Nature. 1965 Oct 2;208(5005):46–48. doi: 10.1038/208046a0. [DOI] [PubMed] [Google Scholar]
- Friedrich B., Magasanik B. Urease of Klebsiella aerogenes: control of its synthesis by glutamine synthetase. J Bacteriol. 1977 Aug;131(2):446–452. doi: 10.1128/jb.131.2.446-452.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Griffith D. P., Musher D. M., Itin C. Urease. The primary cause of infection-induced urinary stones. Invest Urol. 1976 Mar;13(5):346–350. [PubMed] [Google Scholar]
- Griffith D. P., Musher D. M. Prevention of infected urinary stones by urease inhibition. Invest Urol. 1973 Nov;11(3):228–233. [PubMed] [Google Scholar]
- Hamilton-Miller J. M., Gargan R. A. Rapid screening for urease inhibitors. Invest Urol. 1979 Mar;16(5):327–328. [PubMed] [Google Scholar]
- Hase J., Kobashi K. Inhibition of Proteus vulgaris urease by hydroxamic acids. J Biochem. 1967 Sep;62(3):293–299. [PubMed] [Google Scholar]
- Hughes R. B., Katz S. A., Stubbins S. E. Inhibition of urease by metal ions. Enzymologia. 1969 Jun 30;36(6):332–334. [PubMed] [Google Scholar]
- Jerusik R. J., Kadis S., Chapman W. L., Jr, Wooley R. E. Influence of acetohydroxamic acid on experimental Corynebacterium renale pyelonephritis. Can J Microbiol. 1977 Oct;23(10):1448–1455. doi: 10.1139/m77-213. [DOI] [PubMed] [Google Scholar]
- KOBASHI K., HASE J., UEHARA K. Specific inhibition of urease by hydroxamic acids. Biochim Biophys Acta. 1962 Dec 4;65:380–383. doi: 10.1016/0006-3002(62)91067-3. [DOI] [PubMed] [Google Scholar]
- LEAL J. A., VILLANUEVA J. R. An improved selective medium for the formation of ascospores by Aspergillus nidulans. Nature. 1962 Mar 17;193:1106–1106. doi: 10.1038/1931106a0. [DOI] [PubMed] [Google Scholar]
- Lynn K. R. Some properties and purifications of urease. Biochim Biophys Acta. 1967 Sep 12;146(1):205–218. doi: 10.1016/0005-2744(67)90087-3. [DOI] [PubMed] [Google Scholar]
- MacLaren D. M. The significance of urease in proteus pyelonephritis: a bacteriological study. J Pathol Bacteriol. 1968 Jul;96(1):45–56. doi: 10.1002/path.1700960106. [DOI] [PubMed] [Google Scholar]
- Magaña-Plaza I., Montes C., Ruiz-Herrera J. Purification and biochemical characteristics of urease from Proteus rettgeri. Biochim Biophys Acta. 1971 Jul 21;242(1):230–237. doi: 10.1016/0005-2744(71)90103-3. [DOI] [PubMed] [Google Scholar]
- Pianotti R. S., Mohan R. R., Schwartz B. S. Proteus vulgaris urease: in vitro inhibition by urea analogues. Proc Soc Exp Biol Med. 1966 Jun;122(2):506–508. doi: 10.3181/00379727-122-31174. [DOI] [PubMed] [Google Scholar]
- Rosenstein I., Hamilton-Miller J. M., Brumfitt W. The effect of acetohydroxamic acid on the induction of bacterial ureases. Invest Urol. 1980 Sep;18(2):112–114. [PubMed] [Google Scholar]
- SHERLOCK S. Hepatic coma. Annu Rev Med. 1960;11:47–58. doi: 10.1146/annurev.me.11.020160.000403. [DOI] [PubMed] [Google Scholar]