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. 1981 Jul;33(1):223–230. doi: 10.1128/iai.33.1.223-230.1981

Biological activity of Bordetella pertussis in lipopolysaccharide-resistant mice.

C H Wirsing von Koenig, B Heymer, H Hof, H Finger, P Emmerling
PMCID: PMC350680  PMID: 6266965

Abstract

Effects of Bordetella pertussis organisms, such as adjuvanticity, induction of hypersplenia, and leukocytosis as well as modification of nonspecific resistance to infection and typical morphological response of lymphatic organs, were studied in the lipopolysaccharide-resistant C3H/HeJ mouse strain. It was shown that B. pertussis exerted all of these effects in C3H/HeJ mice, although the morphological response, hypersplenia, and modification of resistance to infection with Listeria monocytogenes in such animals were less pronounced than those in lipopolysaccharide-sensitive mouse strains. This indicated that the biological activity of B. pertussis as determined in the present studies, is due partly to structural components other than lipopolysaccharide.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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