Hepatitis-B Vaccination Status Among Dental Surgeons in Benin City, Nigeria

Abstract

Background:

The development of success-oriented hepatitis-B vaccine uptake approach among dental surgeons is dependent on the availability of comprehensive baseline data.

Objective:

To determine the hepatitis-B vaccination status among dental surgeons in Benin City.

Materials and Methods:

This questionnaire-based cross-sectional study of dental surgeons in Benin City was conducted in May 2011. The questionnaire elicited information on demography, occupational risk rating of contracting hepatitis-B infection, hepatitis-B vaccination status, barriers to uptake of hepatitis vaccine, and suggestions on how to improve hepatitis-B vaccination rates among dental surgeons.

Results:

Participation rate in the study was 93.3%. More than half (51.4%) of the respondents were 20–30 years old and 52 (74.3%) were males. The occupational risk of contracting hepatitis-B infection among dental surgeons was rated as either high or very high by 51 (72.9%) of the respondents. Amongst the respondents, 14 (20.0%) had received three doses of the hepatitis-B vaccine, 34 (48.6%) either two doses or a single dose, and 22 (31.4%) were not vaccinated. The major barriers reported among the respondents who were not vaccinated were lack of opportunity and the fear of side effects of the vaccines. The suggested ways to increase the vaccination rate among the respondents in descending order include: Making the vaccine available at no cost (51.4%), educating dentists on the merits of vaccination (17.1%), and using the evidence of vaccination as a requirement for annual practicing license renewal (14.3%) and for the employment of dental surgeons (11.4%) and others (2.9%).

Conclusion:

This study revealed low prevalence of complete hepatitis-B vaccination among the respondents. Improvement in uptake following the respondents’ recommendations will serve as a template in developing success-oriented strategies among stakeholders.

Introduction

Hepatitis-B vaccine, developed for the prevention of hepatitis-B virus infection, is a noninfectious recombinant DNA vaccine produced from genetically engineered yeast named Saccharomyces cerevisiae.[1] Although there has been modification in the production of the vaccine after its initial development in 1981, the complete vaccination still remains the uptake of the recommended three-dose regimen, with the second and third doses being given at 1 and 6 months after the initial dose.[2,3] Despite the availability and recommendation on hepatitis-B vaccination, the vaccination rates among dental professionals have remained consistently low in developing countries. The reasons for the suboptimal hepatitis-B vaccination rates among health workers include lack of opportunity, lack of motivation, lack of information, lack of awareness, non-availability, high cost of the vaccine, fear of side effects, fear of being recognized as a hepatitis-B carrier, lack of perceived need for the vaccine, and erroneous belief of non-susceptibility to the infection.[4–16] There also existed no consensus about vaccination rates among dental professionals in the literature as dental surgeons had higher vaccination rates than dental auxiliaries in some studies[15] while dental auxiliaries had higher vaccination rates than dental surgeons in others.[17]

Although information about hepatitis-B vaccination status of dentists in Nigeria is available from studies conducted among dental professionals as a group[15,18] and dental surgeons in different parts of Nigeria exclusively,[19,20] the gaps in knowledge that motivated this present study exist in four specific areas. Firstly, the data on hepatitis-B vaccination status of dental surgeons in Benin City could not be abstracted from these studies, thereby limiting their utilization in developing success-oriented vaccine uptake approach. Secondly, these reports also lacked details about incomplete and complete hepatitis-B vaccination dose uptake. Thirdly, most of these studies were conducted among dental professionals working in the tertiary dental healthcare facilities while other members of staff of secondary and primary dental healthcare facilities were not studied. Finally, the improvement of uptake of hepatitis-B vaccination study has also been neglected in these studies. The potential risk of acquisition of hepatitis-B infection through occupational exposures to blood and its products among dental surgeons and the significant prevalence of hepatitis-B infection in Benin City[21] are the additional reasons for hepatitis-B vaccination research among dental surgeons practicing in this environment. The objective of the study was to assess the hepatitis-B vaccination status among dental surgeons in Benin City, Edo State, Nigeria.

Materials and Methods

This descriptive cross-sectional study of dental surgeons in Benin City was conducted in May 2011, using pretested, 8-itemed, self-administered questionnaire as the tool of data collection. The questionnaire elicited information on demography, occupational risk rating of contracting hepatitis-B infection, hepatitis-B vaccination status, barriers to uptake, and suggestions on how to improve hepatitis-B vaccination rates among dental surgeons. The hand-delivered questionnaires were distributed to dental surgeons working at the University of Benin Teaching Hospital and Central Hospital, Benin City. Other dental surgeons were given the questionnaire at a dental product launch in Benin City. Participation in the study was voluntary and no incentive was offered. Informed consent was obtained from participants after informing them of the objective of the study. The data collected were subjected to descriptive statistics in the form of frequency and percentages using SPSS version 17.0. Test of association was done using Fisher's exact statistics. P<0.05 was considered to be statistically significant.

Results

Participation rate in the study was 93.3%. More than half (51.4%) of the respondents were in the 20–30 years age group and 52 (74.3%) were males [Table 1]. The occupational risk of contracting hepatitis-B infection among dental professionals was rated as either high or very high by 51 (72.9%) of the respondents [Table 2]. Amongst the respondents, 14 (20.0%) had received three doses of the hepatitis-B vaccine, 34 (48.6%) either two doses or a single dose, and 22 (31.4%) were not vaccinated [Table 3]. The major barriers reported among the respondents who were not vaccinated were lack of opportunity and the fear of the side effects of the vaccine [Table 4]. The suggested ways to increase the vaccination rate among the respondents in descending order include: Making the vaccine available at no cost (51.4%), educating dentists on the merits of vaccination (17.1%), and using the evidence of vaccination as a requirement for annual practicing license renewal (14.3%) and for the employment of dental surgeons (11.4%). Others (2.9%) suggested that reminders to complete the vaccination should be sent and that the vaccines should be made available in more centers [Table 5].

Table 1.

Demographic characteristics of the respondents

Table 2.

Respondents’ rating of occupational risk of Hepatitis-B contagion among dental surgeons

Table 3.

Hepatitis-B vaccination status among the respondents

Table 4.

Reasons for non-vaccination among the unvaccinated respondents

Table 5.

Respondents’ recommendations on ways to increase hepatitis-B vaccination rate among dentists

Discussion

In this study, the perceived occupational risk of contracting hepatitis-B infection among dental surgeons was rated as either high or very high by majority of the respondents. This was comparable to the 78% of Malaysian dental practitioners who believed that their risk of contracting hepatitis B was high or very high[7] and 66.6% among Malaysian dentists.[22] This rating may be rooted on the high transmissibility potential of hepatitis-B virus in comparison to other blood-borne pathogens.[23] The frequent exposure to blood and body fluid of patients and the prevalent inadequate infection control practices noted among dental surgeons in developing countries may have contributed to this level of risk perception among the respondents in this study.

In this study, the percentage of the respondents who had received three doses (complete dose) of the hepatitis-B vaccine is lower than 86% reported among health workers in tertiary care hospital, Karachi;[24] 85.7% reported among dental professionals of the Military Hospital, Riyadh;[25] 73.8%[26] and 74.9% among Brazilian dentists;[10] 60% reported among healthcare worker in Lahore;[12] 56.2% reported among Italian dentists;[27] and 35.9% reported among Lithuanian general dental practitioners.[28] The percentage of complete hepatitis vaccination among dentists in Benin City in this study was also lower than the figures reported in other Nigerian studies. Previously, 53.8% was reported among healthcare workers in a tertiary hospital in southwest Nigeria[28] and 48.1% was reported among dental practitioners in Lagos, Ibadan, Ife, and Benin.[20] It has been reported that healthcare workers in Nigeria, who are expected to have high knowledge of and exposure to hepatitis-B infection, showed the greatest apathy to the vaccination program, and this is a possible explanation for the result from this study.[29] The fact that more than three-quarters of the respondents did not know anybody infected with hepatitis B may have deterred them from viewing this disease as serious, and therefore makes them lack the motivation to be vaccinated. Also, the vaccine was made available to the healthcare workers at no cost in most of the previous studies and this may account for the higher percentage of vaccinated health workers.

This study found a higher level of incomplete vaccination when compared with the results of several other previous studies.[10,12,20,24] It therefore means that dental surgeons should not only be encouraged to receive hepatitis-B vaccine but also be encouraged to complete the dose to ensure the effectiveness of this vaccine. Those with incomplete vaccination status should also be encouraged to have anti-HBs titers measured to determine their level of protection and if there will be a need for a further dose of the vaccine. A few of the respondents in this study recommended that a reminder system should be developed to ensure the complete uptake of the vaccine [Table 5].

The percentage of the respondents who were not vaccinated in this study is comparable to 32% reported among Malaysian dental practitioners,[7] but higher than 27.7% reported among health workers in India,[30] 22% documented among healthcare workers in Lahore,[12] and 10% documented among dentists living in Montes Claros, southeast Brazil.[10] However, it is lower than 50.8% and 37% reported among Lithuanian general dental practitioners[28] and dental healthcare workers in Korea,[31] respectively. The fact that most of the respondents in this study were young and had fewer years of practice may be responsible for the low rate of vaccination as Olubuyide et al.[32] in a study among Nigerian doctors and dentists reported that unvaccinated personnel were more likely to be surgeons or dentists less than 37 years of age and had fewer years of professional activity.

There is an association between hepatitis-B virus infection and lack of hepatitis-B vaccination among healthcare personnel.[32,33] This makes the improvement of hepatitis-B vaccine uptake among the studied dental surgeons very important. In this study, one of the major barriers reported among the unvaccinated respondents was lack of opportunity. This tallied with the findings of Ibekwe and Ibeziako[11] and Okeke et al.[13] who reported lack of opportunity as their major reason for non-vaccination among health workers and medical students in Enugu, southeastern Nigeria. Fear of the side effects of the vaccine was also a major barrier to hepatitis-B vaccination in this study and this is similar to findings of several studies in Greater Glasgow Area Health Board,[5] Malaysia,[7] Rhode Island,[4] and United States.[6] Doebbeling et al.[34] also reported that the concern about vaccine's side effects and problems with vaccine access were primarily related to refusal. This is hinged on the fact that perception of vaccine safety is the most important predictor for acceptance of hepatitis-B vaccination among health workers.[35] Other previously reported reasons like lack of information,[7] lack of perceived need for the vaccine,[6] belief that they were not at risk,[9] and never giving it a thought[13] were also among the findings in this study.

In this study, the most commonly suggested way to increase the vaccination rate among the respondents was making the vaccine available at no cost. Sheikh et al.[12] suggested that hepatitis-B vaccine should be made available to healthcare workers at no cost. McGrane and Staines[14] documented that the provision of free vaccine to healthcare workers had a strong positive influence on their decision to be vaccinated. Educating dentists on the merits of vaccination was the second most commonly suggested way of improving hepatitis-B vaccination among the dental surgeons in this study. This recommendation is expected to reasonably improve uptake since dissemination of information resulted in significantly improved knowledge and attitudes and acceptance rates among hospital personnel in a previous study.[36] Acceptance of vaccination has been said to improve with improved knowledge of hepatitis B and improved confidence in vaccine efficacy and safety among hospital personnel.[37]

The suggestion from this study that evidence of vaccination should be used as a requirement for annual practicing license renewal and employing dentists implies that vaccination should be mandatory. This mandatory recommendation has also been suggested in several studies.[12,15,38] The recommendation was significantly associated with gender, with female dental surgeons recommending mandatory vaccination more than males. The better preventive health practices among females may have inclined them to recommending mandatory vaccination in this study.

Conclusion

This study revealed high perception of occupational risk of hepatitis-B virus infection and low hepatitis-B vaccination among the respondents. It is expected that the combination of the recommendations would overcome all the documented barriers and result in 100% uptake of vaccination among the dental surgeons in Benin City. This will serve as a template in developing success-oriented strategies among stakeholders.