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. 1982 Feb;35(2):437–441. doi: 10.1128/iai.35.2.437-441.1982

Experimental Parainfluenzavirus Infection in Mice: Fatal Illness with Atrophy of Thymus and Spleen in Mice Caused by a Variant of Parainfluenza 3 Virus

Hiroshi Shibuta 1, Akio Adachi 1, Tadahito Kanda 1, Minoru Matumoto 2
PMCID: PMC351058  PMID: 6276302

Abstract

Intracerebral inoculation of the YN strain of parainfluenza 3 virus was found to induce an acute fatal illness characterized by marked thymic and splenic atrophy in newborn mice. Previously we showed that the YN strain contains three distinct plaque-type variants, LT, SC, and M. Of these, the M-type variant induced this fatal illness, whereas the other two variants induced hydrocephalus.

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Selected References

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