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. 1982 Mar;35(3):1147–1150. doi: 10.1128/iai.35.3.1147-1150.1982

Biological activities of toxins A and B of Clostridium difficile.

D M Lyerly, D E Lockwood, S H Richardson, T D Wilkins
PMCID: PMC351167  PMID: 7068215

Abstract

Examination of the biological activities of the two known toxins of Clostridium difficile revealed that one of the toxins (toxin A) elicited a hemorrhagic fluid response in rabbit intestinal loops and a positive fluid response in infant mice. The other toxin (toxin B) did not produce a significant fluid response in either model, although the toxin was more lethal in infant mice. Both toxins elicited erythematous and hemorrhagic skin reactions and increased vascular permeability in rabbit skin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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