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. 1982 Mar;35(3):1151–1154. doi: 10.1128/iai.35.3.1151-1154.1982

Immunochemical and cytotoxic activities of Shigella dysenteriae 1 (shiga) and shiga-like toxins.

A D O'Brien, G D Laveck
PMCID: PMC351168  PMID: 7040247

Abstract

Toxins in culture supernatants and bacterial lysates of S. dysenteriae 1 and S. flexneri were quantitated by a cytotoxicity assay and a newly developed radioimmunoassay. Cytotoxin titers paralleled toxin antigen levels. Thus, variations in cytotoxicity among shigellae probably reflect differences in toxin yield rather than specific activity (cytotoxicity per microgram of toxin antigen).

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Selected References

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