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. 1981 Feb;31(2):828–830. doi: 10.1128/iai.31.2.828-830.1981

Macrophage antimicrobial activity: evidence for participation by lysosomes in the killing of Saccharomyces cerevisiae by normal resident macrophages.

P D Hart
PMCID: PMC351385  PMID: 7012023

Abstract

Ammonium chloride added to normal resident mouse peritoneal macrophages reduced the rate of killing of ingested Saccharomyces cerevisiae. It is suggested that this is attributable to the inhibition by ammonia of phagosome-lysosome fusion or of lysosomal protein degradation and that, consequently, lysosomal mechanisms contribute to the normal killing of these yeasts.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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