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. 2012 Oct 8;28(23):3027–3033. doi: 10.1093/bioinformatics/bts568

Table 1.

Evaluation of type 1 error (500/500 cases/controls and 750/750 cases/controls, 30 rare variants)

MAF α Number of cases/controls DBM
0.01 0.05 500/500 0.051
0.01 0.01 500/500 0.008
0.005 0.05 500/500 0.050
0.005 0.01 500/500 0.015
0.01 0.05 750/750 0.047
0.01 0.01 750/750 0.008
0.005 0.05 750/750 0.050
0.005 0.01 750/750 0.011

Tested at α = 0.05 or α = 0.01, 1000 replicates.