Skip to main content
The Texas Heart Institute Journal logoLink to The Texas Heart Institute Journal
. 1982 Sep;9(3):267–273.

Improved Cardiac Function Following Left Ventricular Aneurysm Resection: Pre- and Postoperative Performance Studies in 150 Patients

David A Ott 1, Roberto Parravacini 1, Denton A Cooley 1, E Gordon Depuey 1, George J Reul 1, J Michael Duncan 1, O Howard Frazier 1, James J Livesay 1
PMCID: PMC351625  PMID: 15226926

Abstract

One hundred fifty patients underwent radionuclide left ventricular performance studies before and one week after resection of a left ventricular aneurysm. The patients were classified according to pre-and postoperative ejection fraction into five classes as follows: Class I > 50%, Class II = 41%-50%, Class III = 31%-40%, Class IV = 21%-30%, and Class V = < 21%. They were also classified into groups according to the size of the aneurysm and wall thickness.

Operative mortality was 4.6% (7/150). One hundred one patients (67%) improved at least one “ejection-fraction class” postoperatively; whereas in a similar group of patients who underwent aortocoronary bypass without left ventricular aneurysm resection, only 42.3% (58/137) improved (p < .01). Preoperatively, ejection fraction was < 40% in 136 patients (90.6%); and postoperatively, it was > 40% in 59 patients (39.3%) (p < .01). Improvement of at least one “ejection-fraction class” occurred in 22 patients (47.8%) with small aneurysms, 54 patients (69.2%) with moderate size aneurysms (p < .05), and 25 patients (96.1%) with large aneurysms (p < .01). Sixty-nine patients (88.4%) with thin-walled aneurysms and 32 patients (44.4%) with thick-walled aneurysms improved (p < .01). Resection of a left ventricular aneurysm improves left ventricular function, particularly in patients with large, thin-walled aneurysms. A less aggressive surgical approach is warranted when dealing with thick-walled akinetic areas as patients with these lesions do not respond well to resection.

Full text

PDF
267

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ABRAMS D. L., EDELIST A., LURIA M. H., MILLER A. J. VENTRICULAR ANEURYSM. A REAPPRAISAL BASED ON A STUDY OF SIXTY-FIVE CONSECUTIVE AUTOPSIED CASES. Circulation. 1963 Feb;27:164–169. doi: 10.1161/01.cir.27.2.164. [DOI] [PubMed] [Google Scholar]
  2. Ahmad M., Dubiel J. P., Verdon T. A., Martin R. H. Technetium 99m stannous pyrophosphate myocardial imaging in patients with and without left ventricular aneurysm. Circulation. 1976 May;53(5):833–838. doi: 10.1161/01.cir.53.5.833. [DOI] [PubMed] [Google Scholar]
  3. Aranda J. M., Befeler B., Thurer R., Vargas A., El-Sherif N., Lazzara R. Long-term clinical and hemodynamic studies after ventricular aneurysmectomy and aorta-coronary bypass. J Thorac Cardiovasc Surg. 1977 May;73(5):772–779. [PubMed] [Google Scholar]
  4. Borer J. S., Bacharach S. L., Green M. V., Kent K. M., Epstein S. E., Johnston G. S. Real-time radionuclide cineangiography in the noninvasive evaluation of global and regional left ventricular function at rest and during exercise in patients with coronary-artery disease. N Engl J Med. 1977 Apr 14;296(15):839–844. doi: 10.1056/NEJM197704142961503. [DOI] [PubMed] [Google Scholar]
  5. Borer J. S., Jacobstein J. G., Bacharach S. L., Green M. V. Detection of left ventricular aneurysm and evaluation of effects of surgical repair: the role of radionuclide cineangiography. Am J Cardiol. 1980 May;45(5):1103–1106. doi: 10.1016/0002-9149(80)90181-2. [DOI] [PubMed] [Google Scholar]
  6. Burton N. A., Stinson E. B., Oyer P. E., Shumway N. E. Left ventricular aneurysm. Preoperative risk factors and long-term postoperative results. J Thorac Cardiovasc Surg. 1979 Jan;77(1):65–75. [PubMed] [Google Scholar]
  7. CHAPMAN D. W., AMAD K., COOLEY D. A. Ventricular aneurysm. Fourteen cases subjected to cardiac bypass repair using the pump oxygenator. Am J Cardiol. 1961 Nov;8:633–648. doi: 10.1016/0002-9149(61)90366-6. [DOI] [PubMed] [Google Scholar]
  8. Cooley D. A., Hallman G. L. Surgical treatment of left ventricular aneurysm: experience with excision of postinfarction lesions in 80 patients. Prog Cardiovasc Dis. 1968 Nov;11(3):222–228. doi: 10.1016/0033-0620(68)90012-1. [DOI] [PubMed] [Google Scholar]
  9. Cooperman M., Stinson E. B., Griepp R. B., Shumway N. E. Survival and function after left ventricular aneurysmectomy. J Thorac Cardiovasc Surg. 1975 Feb;69(2):321–328. [PubMed] [Google Scholar]
  10. Favaloro R. G., Effler D. B., Groves L. K., Westcott R. N., Suarez E., Lozada J. Ventricular aneurysm--clinical experience. Ann Thorac Surg. 1968 Sep;6(3):227–245. doi: 10.1016/s0003-4975(10)66018-3. [DOI] [PubMed] [Google Scholar]
  11. Fisher V. J., Alvarez A. J., Shah A., Dolgin M., Tice D. A. Left ventricular scars. Clinical and haemodynamic results of excision. Br Heart J. 1974 Feb;36(2):132–138. doi: 10.1136/hrt.36.2.132. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Frank G., Klein H., Bednarska E., Gahl K., Flohr E., Trieb G., Borst H. G. Results after resection of postinfarction left ventricular aneurysms. Thorac Cardiovasc Surg. 1980 Dec;28(6):423–427. doi: 10.1055/s-2007-1022444. [DOI] [PubMed] [Google Scholar]
  13. Friedman M. L., Cantor R. E. Reliability of gated heart scintigrams for detection of left-ventricular aneurysm: concise communication. J Nucl Med. 1979 Jul;20(7):720–723. [PubMed] [Google Scholar]
  14. Froehlich R. T., Falsetti H. L., Doty D. B., Marcus M. L. Prospective study of surgery for left ventricular aneurysm. Am J Cardiol. 1980 May;45(5):923–931. doi: 10.1016/0002-9149(80)90158-7. [DOI] [PubMed] [Google Scholar]
  15. Goto T., Jay J. H., Mendez M., Zubiate P., Vanstrom N., Yokoyama T. Resection of postinfarction left ventricular aneurysm with and without revascularization. Arch Surg. 1978 Jul;113(7):817–819. doi: 10.1001/archsurg.1978.01370190039006. [DOI] [PubMed] [Google Scholar]
  16. Hopkins G. B., Kan M. K., Salel A. F. Scintigraphic assessment of left ventricular aneurysms. JAMA. 1978 Nov 10;240(20):2162–2165. [PubMed] [Google Scholar]
  17. Key J. A., Aldridge H. E., MacGregor D. C. The selection of patients for resection of left ventricular aneurysm. J Thorac Cardiovasc Surg. 1968 Oct;56(4):477–483. [PubMed] [Google Scholar]
  18. Kitamura S., Echevarria M., Kay J. H., Krohn B. G., Redington J. V., Mendez A., Zubiate P., Dunne E. F. Left ventricular performance before and after removal of the noncontractile area of the left ventricle and revascularization of the myocardium. Circulation. 1972 May;45(5):1005–1017. doi: 10.1161/01.cir.45.5.1005. [DOI] [PubMed] [Google Scholar]
  19. Kluge T. H., Ullal S. R., Hill J. D., Kerth W. J., Gerbode F. Dyskinesia and aneurysm of the left ventricle. Surgical experience in 36 patients. J Cardiovasc Surg (Torino) 1971 Jul-Aug;12(4):273–280. [PubMed] [Google Scholar]
  20. Loop F. D., Effler D. B., Webster J. S., Groves L. K. Posterior ventricular aneurysms. Etiologic factors and results of surgical treatment. N Engl J Med. 1973 Feb 1;288(5):237–239. doi: 10.1056/NEJM197302012880505. [DOI] [PubMed] [Google Scholar]
  21. Marco J. D., Kaiser G. C., Barner H. E., Codd J. E., Willman V. L. Left ventricular aneurysmectomy. Arch Surg. 1976 Apr;111(4):419–422. doi: 10.1001/archsurg.1976.01360220115019. [DOI] [PubMed] [Google Scholar]
  22. Pavel D. G., Zimmer M., Patterson V. N. In vivo labeling of red blood cells with 99mTc: a new approach to blood pool visualization. J Nucl Med. 1977 Mar;18(3):305–308. [PubMed] [Google Scholar]
  23. Rigo P., Gach J., Mengeot P. H. Pre- and postoperative myocardial and blood pool scans in a case of left ventricular aneurysm: Case report. J Nucl Med. 1975 Nov;16(11):1024–1026. [PubMed] [Google Scholar]
  24. Rigo P., Murray M., Strauss H. W., Pitt B. Scintiphotographic evaluation of patients with suspected left ventricular aneurysm. Circulation. 1974 Nov;50(5):985–991. doi: 10.1161/01.cir.50.5.985. [DOI] [PubMed] [Google Scholar]
  25. Rigo P., Pitt B., Straus H. W. The combined use of Gated Cardiac Blood Pool Scanning and Myocardial Imaging with Postassium-43 in the Evaluation of Patients with Myocardial infarction. Radiology. 1975 May;115(2):387–391. doi: 10.1148/115.2.387. [DOI] [PubMed] [Google Scholar]
  26. Rivera R., Delcan J. L. Factors influencing better results in operation for postinfarction ventricular aneurysms. Ann Thorac Surg. 1979 May;27(5):445–450. doi: 10.1016/s0003-4975(10)63344-9. [DOI] [PubMed] [Google Scholar]
  27. SCHLICHTER J., HELLERSTEIN H. K., KATZ L. N. Aneurysm of the heart: a correlative study of one hundred and two proved cases. Medicine (Baltimore) 1954 Feb;33(1):43–86. [PubMed] [Google Scholar]
  28. Sandiford F. M., Cooley D. A. Resection of left ventricular aneurysm. Report of 277 patients. G Ital Cardiol. 1975;5(2):173–183. [PubMed] [Google Scholar]
  29. Sbokos C. G., Monro J. L., Ross J. K. Elective operations for post-infarction left ventricular aneurysms. Thorax. 1976 Feb;31(1):55–62. doi: 10.1136/thx.31.1.55. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Sesto M., Schwarz F., Thiedemann K. U., Flameng W., Schlepper M. Failure of aneurysmectomy to improve left ventricular function. Br Heart J. 1979 Jan;41(1):79–88. doi: 10.1136/hrt.41.1.79. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Shaw R. C., Ferguson T. B., Weldon C. S., Connors J. P. Left ventricular aneurysm resection: indications and long-term follow-up. Ann Thorac Surg. 1978 Apr;25(4):336–339. doi: 10.1016/s0003-4975(10)63552-7. [DOI] [PubMed] [Google Scholar]
  32. Slutsky R., Karliner J., Ricci D., Kaiser R., Pfisterer M., Gordon D., Peterson K., Ashburn W. Left ventricular volumes by gated equilibrium radionuclide angiography: a new method. Circulation. 1979 Sep;60(3):556–564. doi: 10.1161/01.cir.60.3.556. [DOI] [PubMed] [Google Scholar]
  33. Watson L. E., Dickhaus D. W., Martin R. H. Left ventricular aneurysm. Preoperative hemodynamics, chamber volume, and results of aneurysmectomy. Circulation. 1975 Nov;52(5):868–873. doi: 10.1161/01.cir.52.5.868. [DOI] [PubMed] [Google Scholar]
  34. Winzelberg G. G., Strauss H. W., Bingham J. B., McKusick K. A. Scintigraphic evaluation of left ventricular aneurysm. Am J Cardiol. 1980 Dec 18;46(7):1138–1143. doi: 10.1016/0002-9149(80)90284-2. [DOI] [PubMed] [Google Scholar]
  35. Zaret B. L., Strauss H. W., Hurley P. J., Natarajan T. K., Pitt B. A noninvasive scintiphotographic method for detecting regional ventricular dysfunction in man. N Engl J Med. 1971 May 27;284(21):1165–1170. doi: 10.1056/NEJM197105272842101. [DOI] [PubMed] [Google Scholar]

Articles from Texas Heart Institute Journal are provided here courtesy of Texas Heart Institute

RESOURCES