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. 1984 Dec;11(4):378–384.

Giant Lymph Node Hyperplasia of the Mediastinum (Castleman's Disease): Case Report and Review

Muhammad AK Bhatti 1,2, John W Ferrante 1,2, Isaac Gielchinsky 1,2, John C Norman 1,2
PMCID: PMC351713  PMID: 15226878

Abstract

Giant lymph node hyperplasia is a rare, benign disease involving lymph nodes in various locations, predominantly in the mediastinum. There are two variants: plasma cell (earlier and/or acute) and hyaline-vascular, more chronic with an intermediate transitional type. The usual presentation is a solitary well-circumscribed asymptomatic mass lesion, often attaining large size, with infrequent associated hematologic manifestations. A case of giant lymph node hyperplasia involving the paravertebral superior mediastinum is reported.

Surgical excision was the treatment of choice in a 65-year-old man, and at thoractomy, an encapsulated mass was excised from the posterior superior mediastinum. The patient had an uneventful postoperative course and was discharged on the tenth postoperative day.

Three years later, he is well and employed as a carpenter.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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