Skip to main content
Infection and Immunity logoLink to Infection and Immunity
. 1981 Jan;31(1):500–503. doi: 10.1128/iai.31.1.500-503.1981

Production of heat-labile or heat-stable enterotoxins by strains of Escherichia coli belonging to serogroups O44, O114, and O128.

S M Scotland, N P Day, A Cravioto, L V Thomas, B Rowe
PMCID: PMC351810  PMID: 7012006

Abstract

Strains of Escherichia coli which belong to enteropathogenic serogroups usually fail to produce heat-labile or heat-stable enterotoxins. However, 1 of 34 strains of E. coli O44, 9 of 45 strains of E. coli O114, and 18 of 82 strains of E. coli O128 produced heat-labile or heat-stable enterotoxins. Most enterotoxigenic isolates were from tropical or developing countries; all three enterotoxigenic strains isolated in Britain were from patients returned from abroad. Enterotoxigenic strains were of many different flagellar types. Certain enterotoxigenic strains of E. coli O114 and O128 possessed colonization factor antigen I.

Full text

PDF
500

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dean A. G., Ching Y. C., Williams R. G., Harden L. B. Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu. J Infect Dis. 1972 Apr;125(4):407–411. doi: 10.1093/infdis/125.4.407. [DOI] [PubMed] [Google Scholar]
  2. Donta S. T., Moon H. W., Whipp S. C. Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture. Science. 1974 Jan 25;183(4122):334–336. doi: 10.1126/science.183.4122.334. [DOI] [PubMed] [Google Scholar]
  3. Donta S. T., Wallace R. B., Whipp S. C., Olarte J. Enterotoxigenic Escherichia coli and diarrheal disease in Mexican children. J Infect Dis. 1977 Mar;135(3):482–485. doi: 10.1093/infdis/135.3.482. [DOI] [PubMed] [Google Scholar]
  4. Evans D. G., Evans D. J., Jr New surface-associated heat-labile colonization factor antigen (CFA/II) produced by enterotoxigenic Escherichia coli of serogroups O6 and O8. Infect Immun. 1978 Aug;21(2):638–647. doi: 10.1128/iai.21.2.638-647.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Goldschmidt M. C., DuPont H. L. Enteropathogenic Escherichia coli: lack of correlation of serotype with pathogenicity. J Infect Dis. 1976 Feb;133(2):153–156. doi: 10.1093/infdis/133.2.153. [DOI] [PubMed] [Google Scholar]
  6. Guerrant R. L., Brunton L. L., Schnaitman T. C., Rebhun L. I., Gilman A. G. Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli. Infect Immun. 1974 Aug;10(2):320–327. doi: 10.1128/iai.10.2.320-327.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Guerrant R. L., Moore R. A., Kirschenfeld P. M., Sande M. A. Role of toxigenic and invasive bacteria in acute diarrhea of childhood. N Engl J Med. 1975 Sep 18;293(12):567–572. doi: 10.1056/NEJM197509182931201. [DOI] [PubMed] [Google Scholar]
  8. Gurwith M. J., Wiseman D. A., Chow P. Clinical and laboratory assessment of the pathogenicity of serotyped enteropathogenic Escherichia coli. J Infect Dis. 1977 May;135(5):735–743. [PubMed] [Google Scholar]
  9. Klipstein F. A., Rowe B., Engert R. F., Short H. B., Gross R. J. Enterotoxigenicity of enteropathogenic serotypes of Escherichia coli isolated from infants with epidemic diarrhea. Infect Immun. 1978 Jul;21(1):171–178. doi: 10.1128/iai.21.1.171-178.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Konowalchuk J., Speirs J. I., Stavric S. Vero response to a cytotoxin of Escherichia coli. Infect Immun. 1977 Dec;18(3):775–779. doi: 10.1128/iai.18.3.775-779.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Merson M. H., Morris G. K., Sack D. A., Wells J. G., Feeley J. C., Sack R. B., Creech W. B., Kapikian A. Z., Gangarosa E. J. Travelers' diarrhea in Mexico. A prospective study of physicians and family members attending a congress. N Engl J Med. 1976 Jun 10;294(24):1299–1305. doi: 10.1056/NEJM197606102942401. [DOI] [PubMed] [Google Scholar]
  12. Merson M. H., Orskov F., Orskov I., Sack R. B., Huq I., Koster F. T. Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli. Infect Immun. 1979 Feb;23(2):325–329. doi: 10.1128/iai.23.2.325-329.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Reis M. H., Castro A. F., Toledo M. R., Trabulsi L. R. Production of heat-stable enterotoxin by the O128 serogroup of Escherichia coli. Infect Immun. 1979 Apr;24(1):289–290. doi: 10.1128/iai.24.1.289-290.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Rowe B. The role of Escherichia coli in gastroenteritis. Clin Gastroenterol. 1979 Sep;8(3):625–644. [PubMed] [Google Scholar]
  15. Sack D. A., Kaminsky D. C., Sack R. B., Itotia J. N., Arthur R. R., Kapikian A. Z., Orskov F., Orskov I. Prophylactic doxycycline for travelers' diarrhea. Results of a prospective double-blind study of Peace Corps volunteers in Kenya. N Engl J Med. 1978 Apr 6;298(14):758–763. doi: 10.1056/NEJM197804062981402. [DOI] [PubMed] [Google Scholar]
  16. Sack D. A., Merson M. H., Wells J. G., Sack R. B., Morris G. K. Diarrhoea associated with heat-stable enterotoxin-producing strains of Escherichia coli. Lancet. 1975 Aug 9;2(7928):239–241. doi: 10.1016/s0140-6736(75)90958-7. [DOI] [PubMed] [Google Scholar]
  17. Sack R. B., Froehlich J. L., Zulich A. W., Hidi D. S., Kapikian A. Z., Orskov F., Orskov I., Greenberg H. B. Prophylactic doxycycline for travelers' diarrhea: results of a prospective double-blind study of Peace Corps volunteers in Morocco. Gastroenterology. 1979 Jun;76(6):1368–1373. [PubMed] [Google Scholar]
  18. Wadström T. Relative importance of enterotoxigenic and invasive enteropathogenic bacteria in infantile diarrhoea. Zentralbl Bakteriol Orig A. 1978 Nov;242(1):52–62. [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES