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(A) ESEM images of MCF-7S spheroids after 7 days of culturing taken under a series of magnifications (Scale bar from left to right, 300 μm, 50 μm, 5 μm, 2 μm). (B) TEM images of cells on the outside (a) and inside (b) of the MCF-7 tumor spheroid (Scale bar, 2.0 μm).