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. 1977 Jan;11(1):142–146. doi: 10.1128/aac.11.1.142

Beta-Lactamase Activity in Strains of Bacteroides melaninogenicus and Bacteroides oralis

A A Salyers 1, J Wong 1, T D Wilkins 1
PMCID: PMC351933  PMID: 13705

Abstract

β-Lactamase from strains of Bacteroides melaninogenicus and Bacteroides oralis hydrolyzed penicillin more rapidly than ampicillin or carbenicillin. Cephalothin and a chromogenic cephalosporin (87/312) were also hydrolyzed by the enzyme. Activity was found only in β-lactam-resistant strains, but there was considerable variation in activity among strains having the same minimal inhibitory concentrations of antibiotic. β-Lactamase activity was cell bound and appeared to be tightly associated with the cell envelope since detergents were required to elute this activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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