Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1977 Jan;11(1):176–177. doi: 10.1128/aac.11.1.176

Bactericidal Effects of Combinations of Ampicillin with Anti-R-Plasmid Compounds on Salmonella typhimurium R1+

Fred E Hahn 1, Jennie Ciak 1
PMCID: PMC351940  PMID: 319749

Abstract

Salmonella typhimurium R1+, resistant to 2,500 μg of ampicillin per ml, was rapidly killed by combinations of 60 μg of ampicillin per ml with quinacrine (4 × 10−4 M), ethidium bromide (10−4 M), tilorone (10−4 M), or Nitroakridin 3582 (5 × 10−6 M).

Full text

PDF
176

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Hahn F. E., Ciak J. Elimination of resistance determinants from R-factor R1 by intercalative compounds. Antimicrob Agents Chemother. 1976 Jan;9(1):77–80. doi: 10.1128/aac.9.1.77. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Hahn F. E. Experimental elimination of R factors. Antibiot Chemother (1971) 1975;20:196–226. doi: 10.1159/000398468. [DOI] [PubMed] [Google Scholar]
  3. Richmond M. H., Sykes R. B. The beta-lactamases of gram-negative bacteria and their possible physiological role. Adv Microb Physiol. 1973;9:31–88. doi: 10.1016/s0065-2911(08)60376-8. [DOI] [PubMed] [Google Scholar]
  4. Wolfe A. D., Cook T. M., Hahn F. E. Antibacterial nitroacridine, Nitroakridin 3582: effects on bacterial growth and macromolecular biosynthesis in vivo. J Bacteriol. 1971 Oct;108(1):320–327. doi: 10.1128/jb.108.1.320-327.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES