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. 1977 Mar;11(3):514–520. doi: 10.1128/aac.11.3.514

Mobilization of Morganocin 174 Plasmid and Kinetics of Morganocin Production in Proteus and Escherichia coli Hosts

J A Williams 1
PMCID: PMC352014  PMID: 324393

Abstract

Morganocin 174 is coded by a plasmid, Mor174. The plasmid is not self-transmissible but may be mobilized by resistance factor R772. Morganocin synthesis in all Proteus and Providencia strains carrying Mor174 was characterized by a longer lag period after induction and higher titers than in Escherichia coli B(Mor174). The low titers obtained in E. coli B(Mor174) are due to a heatstable inhibitor produced by this strain. Synthesis of morganocin is not constitutive and may be induced by ultraviolet irradiation or mitomycin C. Morganocin production is not influenced by the growth medium of the organism.

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Selected References

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  1. Ben-Gurion R. Chloramphenicol and puromycin as inducers of colicinogenic bacteria. Biochem Biophys Res Commun. 1970 Sep 30;40(6):1281–1288. doi: 10.1016/0006-291x(70)90005-7. [DOI] [PubMed] [Google Scholar]
  2. COETZEE J. N., SACKS T. G. Transduction of streptomycin resistance in Proteus mirabilis. J Gen Microbiol. 1960 Dec;23:445–455. doi: 10.1099/00221287-23-3-445. [DOI] [PubMed] [Google Scholar]
  3. Coetzee J. N. Chromosome transfer in Proteus mirabilis mediated by hybrid plasmid. J Gen Microbiol. 1975 Jan;86(1):133–146. doi: 10.1099/00221287-86-1-133. [DOI] [PubMed] [Google Scholar]
  4. Coetzee J. N., Smit J. A., Prozesky O. W. Properties of Providence and Proteus morganii transducing phages. J Gen Microbiol. 1966 Aug;44(2):167–176. doi: 10.1099/00221287-44-2-167. [DOI] [PubMed] [Google Scholar]
  5. Delisle A. L. Production of bacteriocins in a liquid medium by Streptococcus mutans. Antimicrob Agents Chemother. 1975 Dec;8(6):707–712. doi: 10.1128/aac.8.6.707. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. GOEBEL W. F., BARRY G. T., SHEDLOVSKY T. Colicine K. I. The production of colicine K in media maintained at constant pH. J Exp Med. 1956 May 1;103(5):577–588. doi: 10.1084/jem.103.5.577. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hardy K. G. Colicinogeny and related phenomena. Bacteriol Rev. 1975 Dec;39(4):464–515. doi: 10.1128/br.39.4.464-515.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hardy K. G., Meynell G. G. A model relating the replication and expression of colicin factor E2-P9. Genet Res. 1972 Dec;20(3):331–334. doi: 10.1017/s0016672300013847. [DOI] [PubMed] [Google Scholar]
  9. Hardy K. G., Meynell G. G., Dowman J. E., Spratt B. G. Two major groups of colicin factors: their evolutionary significance. Mol Gen Genet. 1973 Sep 12;125(3):217–230. doi: 10.1007/BF00270744. [DOI] [PubMed] [Google Scholar]
  10. Hedges R. W. R factors from Proteus mirabilis and P. vulgaris. J Gen Microbiol. 1975 Apr;87(2):301–311. doi: 10.1099/00221287-87-2-301. [DOI] [PubMed] [Google Scholar]
  11. JACOB F., SIMINOVITCH L., WOLLMAN E. Sur la biosynthèse d'une colicine et sur son mode d'action. Ann Inst Pasteur (Paris) 1952 Sep;83(3):295–315. [PubMed] [Google Scholar]
  12. Jesaitis M. A. The nature of colicin K from Proteus mirabilis. J Exp Med. 1970 May 1;131(5):1016–1038. doi: 10.1084/jem.131.5.1016. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Jetten A. M., Vogels G. D. Characterization and extrachromosomal control of bacteriocin production in Staphylococcus aureus. Antimicrob Agents Chemother. 1973 Jul;4(1):49–57. doi: 10.1128/aac.4.1.49. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Jetten A. M., Vogels G. D., de Windt F. Production and purification of a Staphylococcus epidermidis bacteriocin. J Bacteriol. 1972 Oct;112(1):235–242. doi: 10.1128/jb.112.1.235-242.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Kennedy C. K. Induction of colicin production by high temperature or inhibition of protein synthesis. J Bacteriol. 1971 Oct;108(1):10–19. doi: 10.1128/jb.108.1.10-19.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. MONK M., CLOWES R. C. THE REGULATION OF COLICIN SYNTHESIS AND COLICIN FACTOR TRANSFER IN ESCHERICHIA COLI K12. J Gen Microbiol. 1964 Sep;36:385–392. doi: 10.1099/00221287-36-3-385. [DOI] [PubMed] [Google Scholar]
  17. OZEKI H., STOCKER B. A., DE MARGERIE H. Production of colicine by single bacteria. Nature. 1959 Aug 1;184:337–339. doi: 10.1038/184337a0. [DOI] [PubMed] [Google Scholar]
  18. OZEKI H., STOCKER B. A., SMITH S. M. Transmission of colicinogeny between strains of Salmonella typhimurium grown together. J Gen Microbiol. 1962 Sep;28:671–687. doi: 10.1099/00221287-28-4-671. [DOI] [PubMed] [Google Scholar]
  19. Rogers A. H. Effect of the medium on bacteriocin production among strains of Streptococcus mutans. Appl Microbiol. 1972 Aug;24(2):294–295. doi: 10.1128/am.24.2.294-295.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Roth T. F., Helinski D. R. Evidence for circular DNA forms of a bacterial plasmid. Proc Natl Acad Sci U S A. 1967 Aug;58(2):650–657. doi: 10.1073/pnas.58.2.650. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Shapiro L., Agabian-Keshishian N., Hirsch A., Rosen O. M. Effect of dibutyryladenosine 3':5'-cyclic monophosphate on growth and differentiation in Caulobacter crescentus. Proc Natl Acad Sci U S A. 1972 May;69(5):1225–1229. doi: 10.1073/pnas.69.5.1225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Smit J. A., de Klerk H. C., Coetzee J. N. Properties of a Proteus morganii bacteriocin. J Gen Microbiol. 1968 Nov;54(1):67–75. doi: 10.1099/00221287-54-1-67. [DOI] [PubMed] [Google Scholar]
  23. Tagg J. R., Dajani A. S., Wannamaker L. W., Gray E. D. Group A streptococcal bacteriocin. Production, purification, and mode of action. J Exp Med. 1973 Nov 1;138(5):1168–1183. doi: 10.1084/jem.138.5.1168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Timmis K. Purification and characterization of colicin D. J Bacteriol. 1972 Jan;109(1):12–20. doi: 10.1128/jb.109.1.12-20.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]

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