Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1977 Mar;11(3):569–570. doi: 10.1128/aac.11.3.569

Microbial Formation of 4-Thiouracil

L Dolak 1, W T Sokolski 1, S Mizsak 1, D W Stroman 1, O K Sebek 1
PMCID: PMC352023  PMID: 404965

Abstract

A soil organism identified as Streptomyces libani var. soldani was found to produce 4-thiouracil. The product was isolated in a yield of 150 μg/ml of filtered beer and characterized by C-13 magnetic resonance and high-resolution mass spectroscopy. The product has a broad antibacterial spectrum but low specific activity.

Full text

PDF
569

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ELION G. B., BIEBER S., NATHAN H., HITCHINGS G. H. Uracil antagonism and inhibition of mammary adenocarcinoma 755. Cancer Res. 1958 Aug;18(7):802–817. [PubMed] [Google Scholar]
  2. Lipsett M. N. The isolation of 4-thiouridylic acid from the soluble ribonucleic acid of Escherichia coli. J Biol Chem. 1965 Oct;240(10):3975–3978. [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES