Abstract
In the presence of an inhibitory concentration of cerulenin, cells of Staphylococcus aureus can resume growth when supplemented with either a saturated or an unsaturated fatty acid. A requirement for both types of acids for growth could not be demonstrated.
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Selected References
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- Altenbern R. A. Enterotoxin B formation by fermentation mutants of Staphylococcus aureus. Can J Microbiol. 1976 Feb;22(2):182–188. doi: 10.1139/m76-025. [DOI] [PubMed] [Google Scholar]
- Chopra I. Induction of tetracycline resistance in Staphylococcus aureus in the absence of lipid synthesis. J Gen Microbiol. 1975 Dec;91(2):433–436. doi: 10.1099/00221287-91-2-433. [DOI] [PubMed] [Google Scholar]
- Cronan J. E., Jr, Gelmann E. P. Physical properties of membrane lipids: biological relevance and regulation. Bacteriol Rev. 1975 Sep;39(3):232–256. doi: 10.1128/br.39.3.232-256.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- D'Agnolo G., Rosenfeld I. S., Awaya J., Omura S., Vagelos P. R. Inhibition of fatty acid synthesis by the antibiotic cerulenin. Specific inactivation of beta-ketoacyl-acyl carrier protein synthetase. Biochim Biophys Acta. 1973 Nov 29;326(2):155–156. doi: 10.1016/0005-2760(73)90241-5. [DOI] [PubMed] [Google Scholar]
- Goldberg I., Walker J. R., Bloch K. Inhibition of lipid synthesis in Escherichia coli cells by the antibiotic cerulenin. Antimicrob Agents Chemother. 1973 May;3(5):549–554. doi: 10.1128/aac.3.5.549. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Omura S., Katagiri M., Awaya J., Furukawa T., Umezawa I., Oi N., Mizoguchi M., Aoki B., Shindo M. Relationship between the structures of fatty acid amide derivatives and their antimicrobial activities. Antimicrob Agents Chemother. 1974 Aug;6(2):207–215. doi: 10.1128/aac.6.2.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Theodore T. S., Panos C. Protein and fatty acid composition of mesosomal vesicles and plasma membranes of Staphylococcus aureus. J Bacteriol. 1973 Nov;116(2):571–576. doi: 10.1128/jb.116.2.571-576.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wille W., Eisenstadt E., Willecke K. Inhibition of de novo fatty acid synthesis by the antibiotic cerulenin in Bacillus subtilis: effects on citrate-Mg2+ transport and synthesis of macromolecules. Antimicrob Agents Chemother. 1975 Sep;8(3):231–237. doi: 10.1128/aac.8.3.231. [DOI] [PMC free article] [PubMed] [Google Scholar]