Bioidentical hormone therapy

The conclusion of the July Tools for Practice, “that there is no convincing evidence that bioidentical hormones are safer or more effective than synthetic HRT [hormone replacement therapy],”¹ is contradicted by a meta-analysis that concluded “physiological data and clinical outcomes demonstrate that bioidentical hormones are associated with lower risks, including the risk of breast cancer and cardiovascular disease, and are more efficacious than their synthetic and animal-derived counterparts. Until evidence to the contrary, bioidentical hormones remain the preferred method of HRT. Further randomized controlled trials are needed to delineate these differences more clearly.”² I wonder if the authors of the Tools for Practice have reviewed the papers that made up this meta-analysis.