Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1978 Sep;14(3):436–438. doi: 10.1128/aac.14.3.436

In Vitro Activity of Thienamycin

Francis P Tally 1, Nilda V Jacobus 1, Sherwood L Gorbach 1
PMCID: PMC352476  PMID: 708019

Abstract

The in vitro activity of thienamycin was tested against 135 aerobic and anaerobic bacteria. The compound was highly active against resistant gram-negative bacilli and penicillin-resistant Straphylococcus aureus. The antianaerobic spectrum of the drug seemed to be comparable to that of metronidazole.

Full text

PDF
436

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ernst E. C., Berger S., Barza M., Jacobus N. V., Tally F. P. Activity of cefamandole and other cephalosporins against aerobic and anaerobic bacteria. Antimicrob Agents Chemother. 1976 May;9(5):852–855. doi: 10.1128/aac.9.5.852. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Finegold S. M. Therapy for infections due to anaerobic bacteria: an overview. J Infect Dis. 1977 Mar;135 (Suppl):S25–S29. doi: 10.1093/infdis/135.supplement.s25. [DOI] [PubMed] [Google Scholar]
  3. Salaki J. S., Black R., Tally F. P., Kislak J. W. Bacteroides fragilis resistant to the administration of clindamycin. Am J Med. 1976 Mar;60(3):426–428. doi: 10.1016/0002-9343(76)90759-2. [DOI] [PubMed] [Google Scholar]
  4. Spratt B. G., Jobanputra V., Zimmermann W. Binding of thienamycin and clavulanic acid to the penicillin-binding proteins of Escherichia coli K-12. Antimicrob Agents Chemother. 1977 Sep;12(3):406–409. doi: 10.1128/aac.12.3.406. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Sutter V. L., Finegold S. M. Susceptibility of anaerobic bacteria to 23 antimicrobial agents. Antimicrob Agents Chemother. 1976 Oct;10(4):736–752. doi: 10.1128/aac.10.4.736. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Tally F. P., Jacobus N. V., Bartlett J. G., Gorbach S. L. Susceptibility of anaerobes to cefoxitin and other cephalosporins. Antimicrob Agents Chemother. 1975 Feb;7(2):128–132. doi: 10.1128/aac.7.2.128. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES