Abstract
Susceptibility disks impregnated with 35 different antibiotics were assayed by the current Code of Federal Regulations method and by a new method employing an agar overlay. The new method, a simplified analytical procedure, exhibited improvement in zone definition and an increase in dose response. Assays performed by the new method were accurate and precise. The agar overlay technique appears to be superior to the current Code of Federal Regulations method.
Full text
PDF



Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Barry A. L., Garcia F., Thrupp L. D. An improved single-disk method for testing the antibiotic susceptibility of rapidly-growing pathogens. Am J Clin Pathol. 1970 Feb;53(2):149–158. doi: 10.1093/ajcp/53.2.149. [DOI] [PubMed] [Google Scholar]
- Rippere R. A. Effects of paper on performance of antibiotic-impregnated disks. J Pharm Sci. 1978 Mar;67(3):367–371. doi: 10.1002/jps.2600670325. [DOI] [PubMed] [Google Scholar]

