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. 1979 Mar;15(3):379–383. doi: 10.1128/aac.15.3.379

Quantitative Nasal Cultures from Carriers of Staphylococcus aureus: Effects of Oral Therapy with Erythromycin, Rosamicin, and Placebo

Samuel Z Wilson 1, R Russell Martin 1,2, Margaret Putman 2, Stephen B Greenberg 1,2, Richard J Wallace Jr 1,2, Joseph G Jemsek 2
PMCID: PMC352669  PMID: 464564

Abstract

Serial quantitative nasal cultures were performed on 87 healthy nasal carriers of Staphylococcus aureus, who were randomly assigned to 7 days of oral therapy with erythromycin, rosamicin (an investigational macrolide antibiotic), or placebo. Staphylococcal carrier rates decreased during therapy with both antibiotics; however, erythromycin was significantly more effective in lowering carrier rates than was rosamicin. The anti-staphylococcal effects of both antibiotics were similar when the mean numbers of S. aureus isolated from positive cultures during therapy were compared. Side effects to each regimen were minimal.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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