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. Author manuscript; available in PMC: 2012 Dec 27.
Published in final edited form as: JAMA. 2012 Jun 27;307(24):2609–2616. doi: 10.1001/jama.2012.5847

Table 1.

Demographic and Disease Characteristics According to Early Response to Therapy

Complete Response No Complete Response


Characteristic No. of Patients % No. of Patients % P
No. of Patients 47 41

Gender
    Male 35 74 24 59 .17
    Female 12 26 17 41

Race
    Caucasian 40 85 37 90
    African American 4 9 3 7 .53a
    Asian 2 4 0 0
    Other 1 2 1 2

Age
    Median (years) 13.2 14.0 .97
    Range (years) 4.7–20.6 4.4–19.1

Histology
    Nodular sclerosing 11 23 26 63 <.001b
    Mixed cellularity 5 11 5 12
    Lymphocyte rich 2 4 1 2
    Classical, not otherwise specified 3 6 3 7
    Nodular Lymphocyte predominant 26 55 6 15 <.001c

Stage
    IA 27 57 12 29 .010
    IIA 20 43 29 71

Mediastinal mass
    Absent 36 77 17 41 .001
    Present 11 23 24 59

Bulkd
    Absent 43 91 32 78 .13
    Present 4 9 9 22
a

Comparison of Caucasian vs. other races

b

Comparison of nodular sclerosing vs. other histologies

c

Comparison of lymphocyte predominant vs. other histologies

d

Peripheral lymph node disease ≥ 6 cm