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. 1979 Aug;16(2):123–126. doi: 10.1128/aac.16.2.123

Development of Resistance to Amphotericin B in Candida lusitaniae Infecting a Human

D Pappagianis 1, M S Collins 1, R Hector 1, J Remington 2
PMCID: PMC352808  PMID: 290351

Abstract

Candida lusitaniae associated with infection in a patient with acute myelogenous leukemia developed resistance to amphotericin B during systemic treatment of the patient. The organism, when isolated initially, was inhibited by 0.31 μg of amphotericin B per ml in yeast nitrogen base agar, but when isolated (20 days later) just antemortem and postmortem, required 100 and 50 μg/ml, respectively, for complete inhibition at 48 h.

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Selected References

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