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. 1979 Aug;16(2):217–220. doi: 10.1128/aac.16.2.217

In Vitro Susceptibilities of Naegleria fowleri Strain HB-1 to Selected Antimicrobial Agents, Singly and in Combination

Kenneth K Lee 1, Stephen L Karr Jr 2, Ming M Wong 3, Paul D Hoeprich 1
PMCID: PMC352825  PMID: 485131

Abstract

The overall prognosis of primary amoebic meningoencephalitis remains poor. The results of this study support previous finding that amphotericin B is the most efficacious drug against the Naegleria species in in vitro testing. In addition, the methyl ester of amphotericin B, a new derivative, also appears to be an effective agent. Of the drug combinations studied, amphotericin B plus minocycline and amphotericin B plus tetracycline showed synergy. The clinical significance of these findings remains to be determined.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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