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. 1979 Aug;16(2):240–242. doi: 10.1128/aac.16.2.240

Inhibition by Ethambutol of Mycolic Acid Transfer into the Cell Wall of Mycobacterium smegmatis

Kuni Takayama 1, Emma L Armstrong 1, Keith A Kunugi 1, James O Kilburn 2
PMCID: PMC352831  PMID: 485133

Abstract

Ethambutol simultaneously inhibited the transfer (presumably via mycolyl acetyl trehalose) of mycolic acids into the cell wall and stimulated the synthesis of trehalose dimycolates of Mycobacterium smegmatis. Structural similarities of the drug and mycolyl acetyl trehalose suggested that competitive inhibition was involved.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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